Single Mutation Contributes to Fetal Microcephaly in Zika Virus – Infectious Disease Advisor

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Single Mutation Contributes to Fetal Microcephaly in Zika Virus
Infectious Disease Advisor
The researchers found that a single serine to glutamin substitution (S139N) in the viral polyprotein substantially increased Zika virus infectivity in both human and mouse neural progenitor cells. This led to more significant microcephaly in mice



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